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In vivo applications / Behavioural applications
In vivo applications / Monitoring

MultiMouseMonitor

from Phenosys

Activity and movement are fundamental diagnostic parameters of animal behavior. However, measuring long-term individual movement within groups was not possible until recently. The MultiMouseMonitor provides accurate individual movement data in a fully automated way. This is a unique solution for the 24/7 long-term tracking and surveillance of individual animals living in groups which requires no operator attention. This MultiMouseMonitor is equipped with 8 reader grid for Type III cages.

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A sensor plate placed underneath a cage that detects individuals and tracks them as they move through the cage. Automated and long-term assessment of individual activity is made possible without having to place individuals in separate cages. The MultiMouseMonitor utilizes advanced RFID technology.

Features

Based on RFID technology
- The MultiMouseMonitor is based on Radio-frequency identification (RFID) technology identifying and tracking an individual within a group of animals. All animals have to carry subcutaneous transponders. These transponders can be reused and are maintenance-free.
24/7, fully automated
Our powerful AnalyticsM software calculates activity indices, spatial preferences, and roaming entropies.
Two sizes are available: MultiMouseMonitor with 8 reader grid for Type III cages and MultiMouseMonitorXT with 20 reader grid for Type IV cages.

Applications

Measurement of individual locomotor activity and distances.
Ideal for rat and mouse models of hyperactivity, movement disorders (i.e. ADHD, Parkinson’s), neuropathic pain, and arthritis
Determination of individual spatial preferences within a group cage.

Variations

Two sizes are available: MultiMouseMonitor with 8 reader grid for Type III cages and MultiMouseMonitorXT with 20 reader grid for Type IV cages.

Type III cage (for mice): 382 x 220 mm

Type IV cage (for mice or rats): 556 x 334 mm

References

Schwab, K., Frahm, S., Magbagbeolu, M., Horsley, D., Goatman, E.A., Melis, V., Theuring, F., Ishaq, A., Storey, J.M.D., Harrington, C.R., Wischik, C.M., Riedel, G., LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy, European Journal of Pharmacology (2024). https://doi.org/10.1016/j.ejphar.2024.176505

Kaixin Huang, Laura K Milton, Harry Dempsey, Stephen J Power, Kyna-Anne Conn, Zane B Andrews, Claire J Foldi (2023) Rapid, automated and experimenter-free touchscreen testing reveals reciprocal interactions between cognitive flexibility and activity-based anorexia in female rats eLife 12:e84961 https://doi.org/10.7554/eLife.84961

Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y., & Rivalan, M. (2020). Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats. Behavioural brain research, 377, 112188.

Frahm, S., Melis, V., Horsley, D., Rickard, J. E., Riedel, G., Fadda, P., … & Schwab, K. (2018). Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson’s disease. Behavioural Brain Research, 339, 153-168.

Reismann, D., Stefanowski, J., Günther, R., Rakhymzhan, A., Matthys, R., Nützi, R., … & Naundorf, S. (2017). Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature. Nature communications, 8(1), 1-15.

Rivalan, M., Munawar, H., Fuchs, A., & Winter, Y. (2017). An automated, experimenter-free method for the standardised, operant cognitive testing of rats. PloS one, 12(1), e0169476.

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Descriptions