Understanding of the dynamics of neuronal ensembles in the brain is as much important as the examination of the contribution of a single neuron during neuronal processes. State of the art rigs support the idea to examine large neuronal populations. Moreover, these populations tend to be cooperative with each other, but it is still unknown how stable these ensembles and their connections. Dr. Rafael Yuste and his lab’s goal is to understand the long-term stability of these neuronal ensembles in mouse visual cortex. They applied two-photon volumetric calcium microcopy to perform chronic calcium imaging for several weeks. They found visually-evoked ensembles were quite stable. Their results suggest that these neuronal populations implement long-term memories.

 For more information: https://www.biorxiv.org/content/10.1101/2020.10.28.359117v1