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Ex vivo and in vitro applications / Slice perfusion components / Bath temperature controller
In-line Solution Heater
Dual-channel In-line Solution Heater Xchange
Regulate the temperature of the incoming solutions to brain slice chambers and tissue chambers. These In-line Solution Heaters are designed to be used in shielded environments. They do not generate any hum or other noise, so they can be used in any microelectrode laboratory (e.g. patch clamp).
In-line Solution Heaters are the best warming devices of brain slice chambers and living tissue chambers. Chamber heaters regulate the temperature of the whole liquid content of the chamber, except the most important area, above the objective. The objectives are not heated in most cases. That is why immersion objectives behave as heat drains. As a result, the observed cell culture will be much cooler than the surrounding solution. Even the most important area is warmed improperly by chamber heaters. In-line Solution Heaters solve this issue.
The outer diameter of the tube connectors are 1.2 mm. The thickness of the tube walls are 0.114 mm. The internal stainless steel metal tubing is made of a very special material. This kind of steel alloy is fully inert for any biological application.
The internal tubing of the In-line Solution Heaters form Archimedean spirals (also called arithmetic spiral). This geometry of the tube provides a linear reduction in the speed of the solution from the input to the output tube connectors. It is an essential feature as it minimizes the number of oxygen bubbles at the output liquid flow. Because of this construction the working position of the In-line Solution Heater is advisable as perfectly horizontal. The side with the blue factory logo label and the heat sink should be positioned as top side. The input tube connector is the one located next to the mechanical fixing connector. This positioning arrangement is important for proper operation.
There are internal temperature sensors in the In-line Solution Heaters. It is recommended to use them instead of the temperature sensors immersed in the solution bath.
During the construction of the In-line Solution Heaters we have focused on the highest noise suppression, and versatile shielding and grounding possibilities. For this purpose the internal assembly of the In-line Solution Heater units are fully independent. This provides complete freedom to connect them anywhere electrically. The best connection points are the stainless steel tubes, because they are easily accessible, and they are connected to all internal metal parts of In-line Solution Heaters. The tubes can be clamped using crocodile clips. The best point for grounding the heater is the low voltage signal (and local shield) ground point, as close to the chamber as possible. The appropriate ground point should be chosen according to several different aspects. But there are two reasons why it is strongly recommended to connect the In-line Solution Heater to ground: 1) Suppression of hum noise in the shielded environment, 2) Elimination of the parasitic electrochemical (galvanic) potentials between the different metal parts.
The plastic enclosure is not hermetically sealed. Please make sure not to pour liquid on the enclosure. Please do not immerse the equipment in liquid (water, saline or any other solution). The seal of this equipment has limitations; the electronic circuit will go wrong if a corrosive solution diffuses into the plastic case.
Tecnical parameters of the Dual-channel In-line Solution Heater:
- Flow rate: 2 x 7 ml / min (specified for 37 Centigrade at the output tube)
- Internal solution buffer volume: 2 x 5.2 ml
- Hysteresis: less than +/- 0.5 Centigrade
- Outer dimensions of the plastic box: 90 x 50 x 32 mm (excluding the heat sink)
Product Xchange:
Since cell cultures and other biological objects are very sensitive, the In-line Solution Heater should not be used if it is faulty, or contaminated in any way. For faults arising during intended usage we have a special offer, only for our previous customers. If you send your used In-line Solution Heater back, we will replace it for a brand new one. A used In-line Solution Heater can not be repaired, as all the internal parts would have to be replaced. In most cases the plastic enclosure and the electric cable is also worn out. So we can not reuse any part of the old device at all. We welcome used devices because we disassemble them to study the effects of usage on the internal parts. This way we collect valuable information to improve the quality of the product. This replacement possibility is provided at a discounted price.
Descriptions
Regulate the temperature of the incoming solutions to brain slice chambers and tissue chambers. These In-line Solution Heaters are designed to be used in shielded environments. They do not generate any hum or other noise, so they can be used in any microelectrode laboratory (e.g. patch clamp).
In-line Solution Heaters are the best warming devices of brain slice chambers and living tissue chambers. Chamber heaters regulate the temperature of the whole liquid content of the chamber, except the most important area, above the objective. The objectives are not heated in most cases. That is why immersion objectives behave as heat drains. As a result, the observed cell culture will be much cooler than the surrounding solution. Even the most important area is warmed improperly by chamber heaters. In-line Solution Heaters solve this issue.
The outer diameter of the tube connectors are 1.2 mm. The thickness of the tube walls are 0.114 mm. The internal stainless steel metal tubing is made of a very special material. This kind of steel alloy is fully inert for any biological application.
The internal tubing of the In-line Solution Heaters form Archimedean spirals (also called arithmetic spiral). This geometry of the tube provides a linear reduction in the speed of the solution from the input to the output tube connectors. It is an essential feature as it minimizes the number of oxygen bubbles at the output liquid flow. Because of this construction the working position of the In-line Solution Heater is advisable as perfectly horizontal. The side with the blue factory logo label and the heat sink should be positioned as top side. The input tube connector is the one located next to the mechanical fixing connector. This positioning arrangement is important for proper operation.
There are internal temperature sensors in the In-line Solution Heaters. It is recommended to use them instead of the temperature sensors immersed in the solution bath.
During the construction of the In-line Solution Heaters we have focused on the highest noise suppression, and versatile shielding and grounding possibilities. For this purpose the internal assembly of the In-line Solution Heater units are fully independent. This provides complete freedom to connect them anywhere electrically. The best connection points are the stainless steel tubes, because they are easily accessible, and they are connected to all internal metal parts of In-line Solution Heaters. The tubes can be clamped using crocodile clips. The best point for grounding the heater is the low voltage signal (and local shield) ground point, as close to the chamber as possible. The appropriate ground point should be chosen according to several different aspects. But there are two reasons why it is strongly recommended to connect the In-line Solution Heater to ground: 1) Suppression of hum noise in the shielded environment, 2) Elimination of the parasitic electrochemical (galvanic) potentials between the different metal parts.
The plastic enclosure is not hermetically sealed. Please make sure not to pour liquid on the enclosure. Please do not immerse the equipment in liquid (water, saline or any other solution). The seal of this equipment has limitations; the electronic circuit will go wrong if a corrosive solution diffuses into the plastic case.
Tecnical parameters of the Dual-channel In-line Solution Heater:
- Flow rate: 2 x 7 ml / min (specified for 37 Centigrade at the output tube)
- Internal solution buffer volume: 2 x 5.2 ml
- Hysteresis: less than +/- 0.5 Centigrade
- Outer dimensions of the plastic box: 90 x 50 x 32 mm (excluding the heat sink)
Product Xchange:
Since cell cultures and other biological objects are very sensitive, the In-line Solution Heater should not be used if it is faulty, or contaminated in any way. For faults arising during intended usage we have a special offer, only for our previous customers. If you send your used In-line Solution Heater back, we will replace it for a brand new one. A used In-line Solution Heater can not be repaired, as all the internal parts would have to be replaced. In most cases the plastic enclosure and the electric cable is also worn out. So we can not reuse any part of the old device at all. We welcome used devices because we disassemble them to study the effects of usage on the internal parts. This way we collect valuable information to improve the quality of the product. This replacement possibility is provided at a discounted price.
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