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In vivo applications / Electroporators
Constant Current Monopolar Electroporator ST
The traditional way of electroporation is applying of constant voltage pulses on the biological tissue. The advantage of that method is the security, because the target can never be burnt. But the usual constant voltage method has a great drawback, that the output current is unknown. The current is depending on the resistance of the biological tissue and determined by the Ohm's law. In the aspect of electroporation the current is the only important parameter, because the electric charge passed to the target is proportional to the current, not the voltage. All in all, the amount of moving ions in the tissue is proportional to the current. We have developed this product to make you able to apply calibrated amount of electric current during electroporation.
Specifications / Technical Data
- The selectable ranges of the output current:
- 100 µA
- 10 mA
- Compliance voltage: 120 V
- Worst-case amplitude error of the constant current generator: < 5 %
- Nonlinearity of the constant current generator: < 5 %
- Output leakage current is internally trimmed to nearly absolute zero, it is less than 1 µA.
- Output overshoot: 0 (zero)
- Output amplitude in the selected range can be set using a 10-turn calibrated helical potentiometer on the front panel.
- Resolution of the helical potentiometer: 0.1 %
- Protected, 2500 V, optically isolated TTL signal conditioner circuit at the input
- Double security isolation
- External control from any PC based DAQ unit or from the Waveform Generator WFG-3a
- Control input: TTL compatible, 1 unit-load
- Active level at the control input: TTL High
Descriptions
The traditional way of electroporation is applying of constant voltage pulses on the biological tissue. The advantage of that method is the security, because the target can never be burnt. But the usual constant voltage method has a great drawback, that the output current is unknown. The current is depending on the resistance of the biological tissue and determined by the Ohm's law. In the aspect of electroporation the current is the only important parameter, because the electric charge passed to the target is proportional to the current, not the voltage. All in all, the amount of moving ions in the tissue is proportional to the current. We have developed this product to make you able to apply calibrated amount of electric current during electroporation.
Specifications / Technical Data
- The selectable ranges of the output current:
- 100 µA
- 10 mA
- Compliance voltage: 120 V
- Worst-case amplitude error of the constant current generator: < 5 %
- Nonlinearity of the constant current generator: < 5 %
- Output leakage current is internally trimmed to nearly absolute zero, it is less than 1 µA.
- Output overshoot: 0 (zero)
- Output amplitude in the selected range can be set using a 10-turn calibrated helical potentiometer on the front panel.
- Resolution of the helical potentiometer: 0.1 %
- Protected, 2500 V, optically isolated TTL signal conditioner circuit at the input
- Double security isolation
- External control from any PC based DAQ unit or from the Waveform Generator WFG-3a
- Control input: TTL compatible, 1 unit-load
- Active level at the control input: TTL High
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